Ionchannels相关论文
In analyses of protein families that may serve as drug targets,membrane-associated G-protein-coupled receptors(GPCRs)dom......
After spinal cord injury,microglia as the first responders to the lesion display both beneficial and detrimental charact......
MicroRNA is a potential target for therapies to improve the physiological function of skeletal muscl
MicroRNAs can regulate the function of ion channels in many organs. Based on our previous study we propose that miR-142a......
离子通道是极具潜力的药物靶点.近年来,越来越多的新的离子通道靶标在疾病中被发现,比如:疼痛、心血管疾病以及神经系统疾病.尽管......
Bufalin is one of the main pharmacological and toxicological components of Venenum Bufonis and many traditional Chinese ......
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Effects of astragaloside Ⅳ on action potentials and ionic currents in Guinea pig ventricular myocyte
AIM AstragalosideⅣ (AS-Ⅳ) is one of the main active constituents of astragalus membranaceus, the present study is to i......
The delayed rectifier potassium current (IK) is a major outward current responsible for ventricular muscle action potent......
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脑水肿及其导致的颅内压升高是急性缺血性卒中患者的主要死亡原因之一。脑水肿的主要发病机制包括细胞毒性水肿、离子性水肿和血管......
Hydrogen sulfide (H2S) is a well-known toxic gas that has the smell of rotten eggs.This pungent gas is synthesized f......
Voltage-gated sodium (Nay) channels are critical in the generation and transmission of neuronal signals.The crystal ......
Nanopore sensing is developing into a powerful label-free approach to investigate the features of biomolecules at the si......
OBJECTIVE: To review the relationship between calcium ion channel and epilepsy for well investigating the pathogenesis o......
心脏受自主神经包括迷走神经和交感神经的双重支配，近年来的实验及临床研究提示，其在心房颤动(房颤)的发生、发展及维持中起重要作用......
浦肯野纤维是心脏传导系统的最后分支,在心内膜下交织成网,再通过特殊的连接方式与普通心室肌细胞相连,主要功能是迅速将电活动传......
锚蛋白家族是重要的整合蛋白,参与心血管系统中离子通道、跨膜蛋白在细胞膜上的固定及适当表达和功能维持.锚蛋白通路的缺陷可以导......
获得性Brugada综合征是一种除了遗传因素以外还与后天因素有关的离子通道疾病.新近的研究又发现了许多与发病相关的基因和细胞电生......
AIM: To examine the effects of berberine, an isoquinoline alkaloid with a long history used as a tonic remedy for liver ......
酸敏感离子通道(acid-sensing ion channels,ASICs)是神经细胞的非电压门控阳离子通道,广泛分布于中枢及外周神经系统,参与痛觉、......
目的 研究慢性铅染毒对仔鼠海马酸敏感离子通道(ASm)la、2a、2b mRNA和蛋白表达的影响.方法 孕鼠随机分为蒸馏水对照组及0.2%、1.0......
